45100 Biopsy of rectum
Also known as: rectal biopsy, transanal biopsy
Biopsy of rectum via open or transanal approach for tissue sampling to diagnose rectal pathology including inflammation, dysplasia, or neoplasia.
In Plain Language
sampling of rectal tissue for examination
Clinical Context
Used for diagnostic evaluation of rectal lesions, ulceration, or inflammatory changes. Can be obtained via transanal, endoscopic, or open approach.
RVU Breakdown
| Work RVU | 3.94 |
| Total RVU | 3.94 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
As a surgical CPT code, proper documentation must include the operative report detailing the procedure performed, patient positioning, approach, findings, and any complications. This code has a 90-day global period, which includes the day of the procedure, 1 day preoperative, and 90 days of postoperative care. Ensure the diagnosis code (ICD-10) supports medical necessity for the procedure.
How This Code Compares
With a work RVU of 3.94, this code ranks in the 27th percentile among Surgery codes — 2.0x below the median (8.00). The highest wRVU in this category is 106.19.
Specialties
Frequently Asked Questions
What is CPT code 45100?
CPT 45100 (Biopsy of rectum) is a Surgery code. Biopsy of rectum via open or transanal approach for tissue sampling to diagnose rectal pathology including inflammation, dysplasia, or neoplasia.
What is the wRVU value for CPT 45100?
The work RVU for CPT 45100 is 3.94. This code is primarily used by Colorectal Surgery, Gastroenterology. It has a 90-day global period.
When is CPT 45100 used?
Used for diagnostic evaluation of rectal lesions, ulceration, or inflammatory changes. Can be obtained via transanal, endoscopic, or open approach.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.