45388 Colonoscopy with ablation
Also known as: colonoscopy with ablation, colon laser ablation
Colonoscopy with ablation of lesion using electrocautery, laser, cryotherapy, or radiofrequency energy.
In Plain Language
burning or freezing of colon lesion; heat or cold treatment via scope
Clinical Context
Used for palliation of obstructing lesions, destruction of residual adenomatous tissue, treatment of colonic angiodysplasia, or recurrent polyps.
RVU Breakdown
| Work RVU | 4.76 |
| Total RVU | 4.76 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
As a surgical CPT code, proper documentation must include the operative report detailing the procedure performed, patient positioning, approach, findings, and any complications. This code has a 0-day global period, meaning pre- and post-operative E&M visits are billable separately on the same day. Ensure the diagnosis code (ICD-10) supports medical necessity for the procedure.
How This Code Compares
With a work RVU of 4.76, this code ranks in the 32nd percentile among Surgery codes — 1.7x below the median (8.00). The highest wRVU in this category is 106.19.
Specialties
Frequently Asked Questions
What is CPT code 45388?
CPT 45388 (Colonoscopy with ablation) is a Surgery code. Colonoscopy with ablation of lesion using electrocautery, laser, cryotherapy, or radiofrequency energy.
What is the wRVU value for CPT 45388?
The work RVU for CPT 45388 is 4.76. This code is primarily used by Colorectal Surgery, Gastroenterology, General Surgery.
When is CPT 45388 used?
Used for palliation of obstructing lesions, destruction of residual adenomatous tissue, treatment of colonic angiodysplasia, or recurrent polyps.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.