45390 Colonoscopy with resection
Also known as: colonoscopy with endoscopic resection, colon EMR/ESD, colonoscopy with foreign body removal
Colonoscopy with resection of portion of colon via endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD).
In Plain Language
removal of colon segment via scope; endoscopic removal of large lesion
Clinical Context
Performed for large sessile polyps or early-stage colonic malignancies amenable to endoscopic resection without formal colectomy.
RVU Breakdown
| Work RVU | 5.89 |
| Total RVU | 5.89 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
As a surgical CPT code, proper documentation must include the operative report detailing the procedure performed, patient positioning, approach, findings, and any complications. This code has a 0-day global period, meaning pre- and post-operative E&M visits are billable separately on the same day. Ensure the diagnosis code (ICD-10) supports medical necessity for the procedure.
How This Code Compares
With a work RVU of 5.89, this code ranks in the 39th percentile among Surgery codes — 1.4x below the median (8.00). The highest wRVU in this category is 106.19.
Specialties
Frequently Asked Questions
What is CPT code 45390?
CPT 45390 (Colonoscopy with resection) is a Surgery code. Colonoscopy with resection of portion of colon via endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD).
What is the wRVU value for CPT 45390?
The work RVU for CPT 45390 is 5.89. This code is primarily used by Colorectal Surgery, Gastroenterology, General Surgery.
When is CPT 45390 used?
Performed for large sessile polyps or early-stage colonic malignancies amenable to endoscopic resection without formal colectomy.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.