45392 Colonoscopy with endoscopic fnb
Also known as: colonoscopy with ultrasound-guided biopsy, colon EUS-FNA
Colonoscopy with endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for tissue sampling.
In Plain Language
needle biopsy using ultrasound guidance; guided tissue sampling in colon
Clinical Context
Performed for tissue diagnosis of submucosal lesions, lymph nodes, or lesions not amenable to standard endoscopic biopsy.
RVU Breakdown
| Work RVU | 5.36 |
| Total RVU | 5.36 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
As a surgical CPT code, proper documentation must include the operative report detailing the procedure performed, patient positioning, approach, findings, and any complications. This code has a 0-day global period, meaning pre- and post-operative E&M visits are billable separately on the same day. Ensure the diagnosis code (ICD-10) supports medical necessity for the procedure.
How This Code Compares
With a work RVU of 5.36, this code ranks in the 36th percentile among Surgery codes — 1.5x below the median (8.00). The highest wRVU in this category is 106.19.
Specialties
Frequently Asked Questions
What is CPT code 45392?
CPT 45392 (Colonoscopy with endoscopic fnb) is a Surgery code. Colonoscopy with endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for tissue sampling.
What is the wRVU value for CPT 45392?
The work RVU for CPT 45392 is 5.36. This code is primarily used by Colorectal Surgery, Gastroenterology, Pathology.
When is CPT 45392 used?
Performed for tissue diagnosis of submucosal lesions, lymph nodes, or lesions not amenable to standard endoscopic biopsy.
Track This Code in RVU Edge
Log procedures, calculate wRVUs, and benchmark against MGMA data — all in one app.
CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.