46505 Chemodenervation anal muscle
Also known as: Botox injection, anal botox, botulinum toxin injection
Chemodenervation of anal muscles using botulinum toxin. Botox is injected into the anal sphincter to reduce spasticity and relieve anal fissure pain.
In Plain Language
injecting Botox into anal muscles to reduce pain; muscle relaxation injection for anal fissure
Clinical Context
Alternative or adjunct to surgery for chronic anal fissures. Reduces internal sphincter tone, improving blood flow and promoting healing.
RVU Breakdown
| Work RVU | 3.10 |
| Total RVU | 3.10 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
As a surgical CPT code, proper documentation must include the operative report detailing the procedure performed, patient positioning, approach, findings, and any complications. This code has a 10-day global period — follow-up visits within 10 days of the procedure are included in the reimbursement. Ensure the diagnosis code (ICD-10) supports medical necessity for the procedure.
How This Code Compares
With a work RVU of 3.10, this code ranks in the 22nd percentile among Surgery codes — 2.6x below the median (8.00). The highest wRVU in this category is 106.19.
Specialties
Frequently Asked Questions
What is CPT code 46505?
CPT 46505 (Chemodenervation anal muscle) is a Surgery code. Chemodenervation of anal muscles using botulinum toxin. Botox is injected into the anal sphincter to reduce spasticity and relieve anal fissure pain.
What is the wRVU value for CPT 46505?
The work RVU for CPT 46505 is 3.10. This code is primarily used by Colorectal Surgery, General Surgery. It has a 10-day global period.
When is CPT 46505 used?
Alternative or adjunct to surgery for chronic anal fissures. Reduces internal sphincter tone, improving blood flow and promoting healing.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.