58100 Biopsy of uterus lining
Also known as: endometrial biopsy, uterine biopsy
Biopsy of uterus lining (endometrial biopsy) is a procedure to obtain tissue from the endometrium for histopathologic evaluation of abnormal uterine bleeding or malignancy.
In Plain Language
Uterus tissue sampling; Uterus lining biopsy
Clinical Context
Used to evaluate abnormal uterine bleeding, assess endometrial cancer risk, evaluate infertility, or diagnose endometritis. Can be office-based with pipette biopsy or operative under anesthesia.
RVU Breakdown
| Work RVU | 1.18 |
| Total RVU | 1.18 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
As a surgical CPT code, proper documentation must include the operative report detailing the procedure performed, patient positioning, approach, findings, and any complications. This code has a 0-day global period, meaning pre- and post-operative E&M visits are billable separately on the same day. Ensure the diagnosis code (ICD-10) supports medical necessity for the procedure.
How This Code Compares
With a work RVU of 1.18, this code ranks in the 6th percentile among Surgery codes — 6.8x below the median (8.00). The highest wRVU in this category is 106.19.
Specialties
Frequently Asked Questions
What is CPT code 58100?
CPT 58100 (Biopsy of uterus lining) is a Surgery code. Biopsy of uterus lining (endometrial biopsy) is a procedure to obtain tissue from the endometrium for histopathologic evaluation of abnormal uterine bleeding or malignancy.
What is the wRVU value for CPT 58100?
The work RVU for CPT 58100 is 1.18. This code is primarily used by Gynecology, Pathology.
When is CPT 58100 used?
Used to evaluate abnormal uterine bleeding, assess endometrial cancer risk, evaluate infertility, or diagnose endometritis. Can be office-based with pipette biopsy or operative under anesthesia.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.