58321 Artificial insemination
Also known as: intrauterine insemination, artificial insemination, IUI
Artificial insemination is placement of prepared sperm into the uterus or fallopian tubes to facilitate pregnancy in infertility treatment.
In Plain Language
Sperm placement in uterus; Fertility treatment with sperm placement
Clinical Context
Performed for male factor infertility, cervical factor, or unexplained infertility. Often combined with ovulation induction. Timing critical relative to ovulation.
RVU Breakdown
| Work RVU | 0.90 |
| Total RVU | 0.90 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
As a surgical CPT code, proper documentation must include the operative report detailing the procedure performed, patient positioning, approach, findings, and any complications. This code has a 0-day global period, meaning pre- and post-operative E&M visits are billable separately on the same day. Ensure the diagnosis code (ICD-10) supports medical necessity for the procedure.
How This Code Compares
With a work RVU of 0.90, this code ranks in the 4th percentile among Surgery codes — 8.9x below the median (8.00). The highest wRVU in this category is 106.19.
Specialties
Frequently Asked Questions
What is CPT code 58321?
CPT 58321 (Artificial insemination) is a Surgery code. Artificial insemination is placement of prepared sperm into the uterus or fallopian tubes to facilitate pregnancy in infertility treatment.
What is the wRVU value for CPT 58321?
The work RVU for CPT 58321 is 0.90. This code is primarily used by Fertility, Gynecology.
When is CPT 58321 used?
Performed for male factor infertility, cervical factor, or unexplained infertility. Often combined with ovulation induction. Timing critical relative to ovulation.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.