65410 Biopsy of cornea
Also known as: corneal biopsy, keratobiopsy
Biopsy of cornea.
In Plain Language
tissue sample from clear front of eye; taking sample from eye surface for testing
Clinical Context
Diagnostic biopsy for suspected corneal dystrophy, infection, or malignancy. Requires careful technique to avoid scarring of visual axis.
RVU Breakdown
| Work RVU | 1.43 |
| Total RVU | 1.43 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
As a surgical CPT code, proper documentation must include the operative report detailing the procedure performed, patient positioning, approach, findings, and any complications. This code has a 0-day global period, meaning pre- and post-operative E&M visits are billable separately on the same day. Ensure the diagnosis code (ICD-10) supports medical necessity for the procedure.
How This Code Compares
With a work RVU of 1.43, this code ranks in the 8th percentile among Surgery codes — 5.6x below the median (8.00). The highest wRVU in this category is 106.19.
Specialties
Frequently Asked Questions
What is CPT code 65410?
CPT 65410 (Biopsy of cornea) is a Surgery code. Biopsy of cornea.
What is the wRVU value for CPT 65410?
The work RVU for CPT 65410 is 1.43. This code is primarily used by corneal surgery, ophthalmology.
When is CPT 65410 used?
Diagnostic biopsy for suspected corneal dystrophy, infection, or malignancy. Requires careful technique to avoid scarring of visual axis.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.