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J0217 Injection velmanase alfa-tycv 1 milligrams

J Codes (Drugs)

Also known as: velmanase alfa, Alaferovec

Velmanase alfa-tycv injection 1 milligram, an enzyme replacement therapy for alpha-mannosidosis.

In Plain Language

rare genetic disease enzyme treatment; alpha-mannosidosis treatment

Clinical Context

Intravenous enzyme replacement therapy for alpha-mannosidosis. Replaces deficient lysosomal alpha-D-mannosidase, reducing substrate accumulation and symptom progression.

RVU Information

CPT J0217 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.

Specialties

GeneticsNeurologyInternal Medicine

Frequently Asked Questions

What is CPT code J0217?

CPT J0217 (Injection velmanase alfa-tycv 1 milligrams) is a J Codes (Drugs) code. Velmanase alfa-tycv injection 1 milligram, an enzyme replacement therapy for alpha-mannosidosis.

How is J0217 administered?

CPT J0217 is administered by a healthcare provider, typically via injection or infusion. Intravenous enzyme replacement therapy for alpha-mannosidosis. Replaces deficient lysosomal alpha-D-mannosidase, reducing substrate accumulation and symptom progression. It is used by Genetics, Neurology, Internal Medicine.

When is CPT J0217 used?

Intravenous enzyme replacement therapy for alpha-mannosidosis. Replaces deficient lysosomal alpha-D-mannosidase, reducing substrate accumulation and symptom progression.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.