J0220 Alglucosidase alfa injection
Also known as: alglucosidase alfa, Myozyme
Alglucosidase alfa injection, a recombinant enzyme replacement therapy for Pompe disease.
In Plain Language
muscle disease enzyme treatment; Pompe disease therapy
Clinical Context
Intravenous enzyme replacement for Pompe disease (acid alpha-glucosidase deficiency). Replaces deficient enzyme, reducing glycogen accumulation in muscles and tissues.
RVU Information
CPT J0220 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J0220?
CPT J0220 (Alglucosidase alfa injection) is a J Codes (Drugs) code. Alglucosidase alfa injection, a recombinant enzyme replacement therapy for Pompe disease.
How is J0220 administered?
CPT J0220 is administered by a healthcare provider, typically via injection or infusion. Intravenous enzyme replacement for Pompe disease (acid alpha-glucosidase deficiency). Replaces deficient enzyme, reducing glycogen accumulation in muscles and tissues. It is used by Genetics, Neurology, Internal Medicine.
When is CPT J0220 used?
Intravenous enzyme replacement for Pompe disease (acid alpha-glucosidase deficiency). Replaces deficient enzyme, reducing glycogen accumulation in muscles and tissues.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.