Home
Career Stage
Medical Students Residents Attendings CPT Codes Resources Blog Support

J0490 Belimumab injection

J Codes (Drugs)

Also known as: belimumab, Benlysta

Belimumab injection, a B-lymphocyte stimulator inhibitor for systemic lupus erythematosus.

In Plain Language

lupus treatment injection; autoimmune disease therapy

Clinical Context

Intravenous monoclonal antibody against B-lymphocyte stimulator (BLyS) for moderate-to-severe systemic lupus erythematosus. Reduces lupus activity.

RVU Information

CPT J0490 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.

Specialties

RheumatologyInternal MedicineImmunology

Frequently Asked Questions

What is CPT code J0490?

CPT J0490 (Belimumab injection) is a J Codes (Drugs) code. Belimumab injection, a B-lymphocyte stimulator inhibitor for systemic lupus erythematosus.

How is J0490 administered?

CPT J0490 is administered by a healthcare provider, typically via injection or infusion. Intravenous monoclonal antibody against B-lymphocyte stimulator (BLyS) for moderate-to-severe systemic lupus erythematosus. Reduces lupus activity. It is used by Rheumatology, Internal Medicine, Immunology.

When is CPT J0490 used?

Intravenous monoclonal antibody against B-lymphocyte stimulator (BLyS) for moderate-to-severe systemic lupus erythematosus. Reduces lupus activity.

Track This Code in RVU Edge

Log procedures, calculate wRVUs, and benchmark against MGMA data — all in one app.

CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.