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J0491 Injection anifrolumab-fnia 1mg

J Codes (Drugs)

Also known as: anifrolumab, Saphnelo

Anifrolumab-fnia injection 1 milligram, an interferon-alpha receptor antagonist for systemic lupus erythematosus.

In Plain Language

lupus treatment injection; interferon blocking therapy

Clinical Context

Intravenous monoclonal antibody blocking interferon-alpha receptor for moderate-to-severe systemic lupus erythematosus with active skin and joint involvement.

RVU Information

CPT J0491 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.

Specialties

RheumatologyInternal MedicineImmunology

Frequently Asked Questions

What is CPT code J0491?

CPT J0491 (Injection anifrolumab-fnia 1mg) is a J Codes (Drugs) code. Anifrolumab-fnia injection 1 milligram, an interferon-alpha receptor antagonist for systemic lupus erythematosus.

How is J0491 administered?

CPT J0491 is administered by a healthcare provider, typically via injection or infusion. Intravenous monoclonal antibody blocking interferon-alpha receptor for moderate-to-severe systemic lupus erythematosus with active skin and joint involvement. It is used by Rheumatology, Internal Medicine, Immunology.

When is CPT J0491 used?

Intravenous monoclonal antibody blocking interferon-alpha receptor for moderate-to-severe systemic lupus erythematosus with active skin and joint involvement.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.