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J0558 Peng benzathine/procaine injection

J Codes (Drugs)

Also known as: penicillin G benzathine/procaine combo, mixed penicillin G

Penicillin G benzathine/procaine combination injection for intramuscular administration, a long-acting penicillin formulation for systemic infection treatment.

In Plain Language

long-acting antibiotic shot; mixed penicillin injection

Clinical Context

Used for treatment of syphilis, streptococcal pharyngitis, and other susceptible infections requiring prolonged penicillin levels. The benzathine component provides extended duration.

RVU Information

CPT J0558 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.

Specialties

infectious diseaseprimary caredermatology

Frequently Asked Questions

What is CPT code J0558?

CPT J0558 (Peng benzathine/procaine injection) is a J Codes (Drugs) code. Penicillin G benzathine/procaine combination injection for intramuscular administration, a long-acting penicillin formulation for systemic infection treatment.

How is J0558 administered?

CPT J0558 is administered by a healthcare provider, typically via injection or infusion. Used for treatment of syphilis, streptococcal pharyngitis, and other susceptible infections requiring prolonged penicillin levels. The benzathine component provides extended duration. It is used by infectious disease, primary care, dermatology.

When is CPT J0558 used?

Used for treatment of syphilis, streptococcal pharyngitis, and other susceptible infections requiring prolonged penicillin levels. The benzathine component provides extended duration.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.