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J0561 Penicillin g benzathine injection

J Codes (Drugs)

Also known as: penicillin G benzathine, benzathine penicillin, Bicillin

Penicillin G benzathine injection for intramuscular administration, a long-acting penicillin formulation providing sustained antibiotic levels for systemic infections.

In Plain Language

long-acting penicillin shot; strep throat treatment

Clinical Context

Primary indication is treatment of group A streptococcal pharyngitis and prophylaxis of rheumatic fever. Also used for syphilis and other susceptible bacterial infections requiring extended antibiotic exposure.

RVU Information

CPT J0561 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.

Specialties

primary careinfectious diseasepediatrics

Frequently Asked Questions

What is CPT code J0561?

CPT J0561 (Penicillin g benzathine injection) is a J Codes (Drugs) code. Penicillin G benzathine injection for intramuscular administration, a long-acting penicillin formulation providing sustained antibiotic levels for systemic infections.

How is J0561 administered?

CPT J0561 is administered by a healthcare provider, typically via injection or infusion. Primary indication is treatment of group A streptococcal pharyngitis and prophylaxis of rheumatic fever. Also used for syphilis and other susceptible bacterial infections requiring extended antibiotic exposure. It is used by primary care, infectious disease, pediatrics.

When is CPT J0561 used?

Primary indication is treatment of group A streptococcal pharyngitis and prophylaxis of rheumatic fever. Also used for syphilis and other susceptible bacterial infections requiring extended antibiotic exposure.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.