J0641 Injection levoleucovorin not otherwise specified 0.5mg
Also known as: levoleucovorin, L-leucovorin, levo-folinic acid
Levoleucovorin injection, not otherwise specified, 0.5 milligrams, the biologically active levorotatory form of leucovorin for chemotherapy rescue.
In Plain Language
active form chemotherapy rescue medication; folate supplement injection
Clinical Context
Active levorotatory form of leucovorin with higher biological activity, requiring lower doses than racemic leucovorin. Used for methotrexate rescue and as adjunct to fluorouracil chemotherapy.
RVU Information
CPT J0641 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J0641?
CPT J0641 (Injection levoleucovorin not otherwise specified 0.5mg) is a J Codes (Drugs) code. Levoleucovorin injection, not otherwise specified, 0.5 milligrams, the biologically active levorotatory form of leucovorin for chemotherapy rescue.
How is J0641 administered?
CPT J0641 is administered by a healthcare provider, typically via injection or infusion. Active levorotatory form of leucovorin with higher biological activity, requiring lower doses than racemic leucovorin. Used for methotrexate rescue and as adjunct to fluorouracil chemotherapy. It is used by oncology, hematology, hospital medicine.
When is CPT J0641 used?
Active levorotatory form of leucovorin with higher biological activity, requiring lower doses than racemic leucovorin. Used for methotrexate rescue and as adjunct to fluorouracil chemotherapy.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.