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J2508 Pegunigalsidase alfa-iwxj

J Codes (Drugs)

Also known as: pegunigalsidase, nexvirome

Injection of pegunigalsidase alfa-iwxj (Nexvirome), a pegylated enzyme for treatment of Gaucher disease type 1, a lysosomal storage disorder.

In Plain Language

rare genetic disease treatment; enzyme replacement

Clinical Context

Used for long-term enzyme replacement therapy in patients with Gaucher disease type 1 to reduce organomegaly and hematologic abnormalities.

RVU Information

CPT J2508 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.

Specialties

HematologyGenetic Medicine

Frequently Asked Questions

What is CPT code J2508?

CPT J2508 (Pegunigalsidase alfa-iwxj) is a J Codes (Drugs) code. Injection of pegunigalsidase alfa-iwxj (Nexvirome), a pegylated enzyme for treatment of Gaucher disease type 1, a lysosomal storage disorder.

How is J2508 administered?

CPT J2508 is administered by a healthcare provider, typically via injection or infusion. Used for long-term enzyme replacement therapy in patients with Gaucher disease type 1 to reduce organomegaly and hematologic abnormalities. It is used by Hematology, Genetic Medicine.

When is CPT J2508 used?

Used for long-term enzyme replacement therapy in patients with Gaucher disease type 1 to reduce organomegaly and hematologic abnormalities.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.