J3385 Velaglucerase alfa
Also known as: velaglucerase alfa, VPRIV, enzyme replacement therapy
Velaglucerase alfa injection is a recombinant enzyme replacement therapy used for Gaucher disease Type 1 treatment.
In Plain Language
genetic storage disease treatment; enzyme replacement infusion
Clinical Context
Used in Gaucher disease Type 1 for enzyme replacement therapy. Recombinant glucocerebrosidase that reduces hepatosplenomegaly and hematologic abnormalities. Administered intravenously every 2 weeks.
RVU Information
CPT J3385 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J3385?
CPT J3385 (Velaglucerase alfa) is a J Codes (Drugs) code. Velaglucerase alfa injection is a recombinant enzyme replacement therapy used for Gaucher disease Type 1 treatment.
How is J3385 administered?
CPT J3385 is administered by a healthcare provider, typically via injection or infusion. Used in Gaucher disease Type 1 for enzyme replacement therapy. Recombinant glucocerebrosidase that reduces hepatosplenomegaly and hematologic abnormalities. Administered intravenously every 2 weeks. It is used by Hematology/Oncology, Rare Disease Specialists, Genetic Medicine.
When is CPT J3385 used?
Used in Gaucher disease Type 1 for enzyme replacement therapy. Recombinant glucocerebrosidase that reduces hepatosplenomegaly and hematologic abnormalities. Administered intravenously every 2 weeks.
Track This Code in RVU Edge
Log procedures, calculate wRVUs, and benchmark against MGMA data — all in one app.
CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.