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81288 Mlh1 gene

Pathology & Lab

Also known as: MLH1 mutation test, Lynch syndrome genetic testing

Mutator S Homolog 1 (MLH1) gene mutation analysis to detect variants associated with Lynch syndrome and colorectal cancer predisposition.

In Plain Language

Colorectal cancer predisposition test; Lynch syndrome screening

Clinical Context

Detects MLH1 mutations causing Lynch syndrome, an inherited cancer predisposition syndrome. Critical for cancer screening, prevention, and family planning.

RVU Information

CPT 81288 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.

Billing & Documentation

Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.

How This Code Compares

This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.

Specialties

PathologyOncologyGastroenterology

Frequently Asked Questions

What is CPT code 81288?

CPT 81288 (Mlh1 gene) is a Pathology & Lab code. Mutator S Homolog 1 (MLH1) gene mutation analysis to detect variants associated with Lynch syndrome and colorectal cancer predisposition.

Who uses CPT code 81288?

CPT 81288 is used by Pathology, Oncology, Gastroenterology. Detects MLH1 mutations causing Lynch syndrome, an inherited cancer predisposition syndrome. Critical for cancer screening, prevention, and family planning.

When is CPT 81288 used?

Detects MLH1 mutations causing Lynch syndrome, an inherited cancer predisposition syndrome. Critical for cancer screening, prevention, and family planning.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.