81294 Mlh1 gene dup/delete variant
Also known as: MLH1 copy number analysis, MLH1 deletion duplication testing
Mutator S Homolog 1 (MLH1) gene duplication and deletion variant analysis to identify copy number variations in Lynch syndrome.
In Plain Language
MLH1 gene copy number test; Lynch syndrome copy variation test
Clinical Context
Detects MLH1 deletions and duplications accounting for 10-15% of Lynch syndrome cases, improving diagnostic yield when sequencing is negative.
RVU Information
CPT 81294 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.
Specialties
Frequently Asked Questions
What is CPT code 81294?
CPT 81294 (Mlh1 gene dup/delete variant) is a Pathology & Lab code. Mutator S Homolog 1 (MLH1) gene duplication and deletion variant analysis to identify copy number variations in Lynch syndrome.
Who uses CPT code 81294?
CPT 81294 is used by Pathology, Oncology, Gastroenterology. Detects MLH1 deletions and duplications accounting for 10-15% of Lynch syndrome cases, improving diagnostic yield when sequencing is negative.
When is CPT 81294 used?
Detects MLH1 deletions and duplications accounting for 10-15% of Lynch syndrome cases, improving diagnostic yield when sequencing is negative.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.