81301 Microsatellite instability
Also known as: MSI testing, microsatellite instability analysis
Microsatellite instability analysis in neoplastic specimens to detect mismatch repair deficiency associated with Lynch syndrome and colorectal cancer.
In Plain Language
Lynch syndrome cancer test; Colon cancer genetic marker
Clinical Context
Detects microsatellite instability indicating mismatch repair deficiency in tumors. Used for Lynch syndrome diagnosis and colorectal cancer prognosis.
RVU Information
CPT 81301 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.
Specialties
Frequently Asked Questions
What is CPT code 81301?
CPT 81301 (Microsatellite instability) is a Pathology & Lab code. Microsatellite instability analysis in neoplastic specimens to detect mismatch repair deficiency associated with Lynch syndrome and colorectal cancer.
Who uses CPT code 81301?
CPT 81301 is used by Pathology, Oncology, Gastroenterology. Detects microsatellite instability indicating mismatch repair deficiency in tumors. Used for Lynch syndrome diagnosis and colorectal cancer prognosis.
When is CPT 81301 used?
Detects microsatellite instability indicating mismatch repair deficiency in tumors. Used for Lynch syndrome diagnosis and colorectal cancer prognosis.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.