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81427 Genome re-evaluation

Pathology & Lab

Also known as: genome re-evaluation, genome reanalysis

Whole genome sequence re-evaluation for previously analyzed patient for genetic disease reevaluation.

In Plain Language

second analysis of genetic test

Clinical Context

Reanalysis of prior whole genome sequencing with updated variant interpretation databases; identifies previously unrecognized disease-causing variants.

RVU Information

CPT 81427 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.

Billing & Documentation

Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.

How This Code Compares

This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.

Specialties

geneticsmolecular pathologyclinical genetics

Frequently Asked Questions

What is CPT code 81427?

CPT 81427 (Genome re-evaluation) is a Pathology & Lab code. Whole genome sequence re-evaluation for previously analyzed patient for genetic disease reevaluation.

Who uses CPT code 81427?

CPT 81427 is used by genetics, molecular pathology, clinical genetics. Reanalysis of prior whole genome sequencing with updated variant interpretation databases; identifies previously unrecognized disease-causing variants.

When is CPT 81427 used?

Reanalysis of prior whole genome sequencing with updated variant interpretation databases; identifies previously unrecognized disease-causing variants.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.