84165 Protein e-phoresis serum
Pathology & Lab
Also known as: serum protein electrophoresis, SPEP, protein fractionation
Electrophoresis of serum proteins separating and quantifying albumin, alpha-1, alpha-2, beta, and gamma globulins.
Clinical Context
Evaluates monoclonal proteins (multiple myeloma), immunoglobulin patterns, and protein composition; abnormal gamma spike suggests plasma cell disorder.
RVU Breakdown
| Work RVU | 0.37 |
| Practice Expense RVU | 0.00 |
| Malpractice RVU | 0.00 |
| Total RVU | 0.37 |
Est. Medicare Payment
$12.36
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Specialties
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.