86335 Immunfix e-phorsis/urine/csf
Also known as: Urine immunofix, CSF immunofix
Immunofixation electrophoresis of urine and cerebrospinal fluid identifies immunoglobulin abnormalities and light chains in non-serum specimens.
In Plain Language
Body fluid protein characterization; Light chain detection
Clinical Context
Used to characterize monoclonal proteins in urine (light chains in myeloma) and cerebrospinal fluid. Provides specific immunoglobulin typing.
RVU Breakdown
| Work RVU | 0.37 |
| Total RVU | 0.37 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
With a work RVU of 0.37, this code ranks in the 29th percentile among Pathology & Lab codes — 1.8x below the median (0.68). The highest wRVU in this category is 2.78.
Specialties
Frequently Asked Questions
What is CPT code 86335?
CPT 86335 (Immunfix e-phorsis/urine/csf) is a Pathology & Lab code. Immunofixation electrophoresis of urine and cerebrospinal fluid identifies immunoglobulin abnormalities and light chains in non-serum specimens.
Who uses CPT code 86335?
CPT 86335 is used by Hematology, Clinical Pathology, Hemato-Oncology. Used to characterize monoclonal proteins in urine (light chains in myeloma) and cerebrospinal fluid. Provides specific immunoglobulin typing.
When is CPT 86335 used?
Used to characterize monoclonal proteins in urine (light chains in myeloma) and cerebrospinal fluid. Provides specific immunoglobulin typing.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.