88304 Tissue examination by pathologist
Also known as: tissue exam, histologic examination
Microscopic examination of tissue sections (5 to 8 blocks) by a pathologist with increased complexity from larger specimen volume.
In Plain Language
microscopic tissue examination; pathology analysis
Clinical Context
Diagnostic examination of larger surgical specimens or multiple biopsies requiring examination of 5-8 tissue blocks.
RVU Breakdown
| Work RVU | 0.21 |
| Total RVU | 0.21 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
With a work RVU of 0.21, this code ranks in the 3rd percentile among Pathology & Lab codes — 3.2x below the median (0.68). The highest wRVU in this category is 2.78.
Specialties
Frequently Asked Questions
What is CPT code 88304?
CPT 88304 (Tissue examination by pathologist) is a Pathology & Lab code. Microscopic examination of tissue sections (5 to 8 blocks) by a pathologist with increased complexity from larger specimen volume.
Who uses CPT code 88304?
CPT 88304 is used by Surgical Pathology, Pathology. Diagnostic examination of larger surgical specimens or multiple biopsies requiring examination of 5-8 tissue blocks.
When is CPT 88304 used?
Diagnostic examination of larger surgical specimens or multiple biopsies requiring examination of 5-8 tissue blocks.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.