88305 Tissue examination by pathologist
Also known as: tissue exam, histopathology
Microscopic examination of tissue sections (9 to 15 blocks) by a pathologist representing moderate to significant specimen complexity.
In Plain Language
detailed tissue examination; comprehensive pathology analysis
Clinical Context
Moderate complexity diagnostic examination for larger surgical specimens such as total thyroidectomies, hysterectomies, or complex organ resections.
RVU Breakdown
| Work RVU | 0.73 |
| Total RVU | 0.73 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
With a work RVU of 0.73, this code ranks in the 60th percentile among Pathology & Lab codes — 1.1x the median (0.68). The highest wRVU in this category is 2.78.
Specialties
Frequently Asked Questions
What is CPT code 88305?
CPT 88305 (Tissue examination by pathologist) is a Pathology & Lab code. Microscopic examination of tissue sections (9 to 15 blocks) by a pathologist representing moderate to significant specimen complexity.
Who uses CPT code 88305?
CPT 88305 is used by Surgical Pathology, Pathology. Moderate complexity diagnostic examination for larger surgical specimens such as total thyroidectomies, hysterectomies, or complex organ resections.
When is CPT 88305 used?
Moderate complexity diagnostic examination for larger surgical specimens such as total thyroidectomies, hysterectomies, or complex organ resections.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.