88380 Microdissection laser
Also known as: microdissection laser, laser capture microdissection, LCM
Laser-assisted microdissection technique to isolate specific cells or tissue regions from a specimen for molecular analysis.
In Plain Language
laser-cut tissue isolation; cell selection with laser
Clinical Context
Precision isolation of specific cell populations or tissue regions using laser technology for downstream molecular testing.
RVU Breakdown
| Work RVU | 1.11 |
| Total RVU | 1.11 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
With a work RVU of 1.11, this code ranks in the 80th percentile among Pathology & Lab codes — 1.6x the median (0.68). The highest wRVU in this category is 2.78.
Specialties
Frequently Asked Questions
What is CPT code 88380?
CPT 88380 (Microdissection laser) is a Pathology & Lab code. Laser-assisted microdissection technique to isolate specific cells or tissue regions from a specimen for molecular analysis.
Who uses CPT code 88380?
CPT 88380 is used by Pathology, Molecular Pathology. Precision isolation of specific cell populations or tissue regions using laser technology for downstream molecular testing.
When is CPT 88380 used?
Precision isolation of specific cell populations or tissue regions using laser technology for downstream molecular testing.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.