88381 Microdissection manual
Also known as: microdissection manual, hand microdissection
Manual microdissection technique using microinstruments to isolate specific cells or tissue regions for molecular analysis.
In Plain Language
hand-cut tissue isolation; manual cell selection
Clinical Context
Manual isolation of specific cell populations or tissue regions using microtools for molecular testing or specialized diagnostic analysis.
RVU Breakdown
| Work RVU | 0.52 |
| Total RVU | 0.52 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
With a work RVU of 0.52, this code ranks in the 39th percentile among Pathology & Lab codes — 1.3x below the median (0.68). The highest wRVU in this category is 2.78.
Specialties
Frequently Asked Questions
What is CPT code 88381?
CPT 88381 (Microdissection manual) is a Pathology & Lab code. Manual microdissection technique using microinstruments to isolate specific cells or tissue regions for molecular analysis.
Who uses CPT code 88381?
CPT 88381 is used by Pathology, Molecular Pathology. Manual isolation of specific cell populations or tissue regions using microtools for molecular testing or specialized diagnostic analysis.
When is CPT 88381 used?
Manual isolation of specific cell populations or tissue regions using microtools for molecular testing or specialized diagnostic analysis.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.