54100 Biopsy of penis
Also known as: penile biopsy, office biopsy
Surgical biopsy of the penis, typically a small tissue sample obtained in the office or outpatient setting.
In Plain Language
taking tissue sample from penis
Clinical Context
Used to diagnose suspicious lesions, infections, or dermatologic conditions of penis. Office-based with minimal anesthesia.
RVU Breakdown
| Work RVU | 1.85 |
| Total RVU | 1.85 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
As a surgical CPT code, proper documentation must include the operative report detailing the procedure performed, patient positioning, approach, findings, and any complications. This code has a 0-day global period, meaning pre- and post-operative E&M visits are billable separately on the same day. Ensure the diagnosis code (ICD-10) supports medical necessity for the procedure.
How This Code Compares
With a work RVU of 1.85, this code ranks in the 12th percentile among Surgery codes — 4.3x below the median (8.00). The highest wRVU in this category is 106.19.
Specialties
Frequently Asked Questions
What is CPT code 54100?
CPT 54100 (Biopsy of penis) is a Surgery code. Surgical biopsy of the penis, typically a small tissue sample obtained in the office or outpatient setting.
What is the wRVU value for CPT 54100?
The work RVU for CPT 54100 is 1.85. This code is primarily used by Urology, Surgical Pathology.
When is CPT 54100 used?
Used to diagnose suspicious lesions, infections, or dermatologic conditions of penis. Office-based with minimal anesthesia.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.