54105 Biopsy of penis
Also known as: penile biopsy under anesthesia, formal biopsy
Surgical biopsy of the penis performed under general anesthesia, allowing deeper or more extensive tissue sampling.
In Plain Language
taking tissue sample from penis under anesthesia
Clinical Context
Used when office biopsy insufficient or lesion located deeper. Allows adequate tissue sampling for diagnosis.
RVU Breakdown
| Work RVU | 3.45 |
| Total RVU | 3.45 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
As a surgical CPT code, proper documentation must include the operative report detailing the procedure performed, patient positioning, approach, findings, and any complications. This code has a 10-day global period — follow-up visits within 10 days of the procedure are included in the reimbursement. Ensure the diagnosis code (ICD-10) supports medical necessity for the procedure.
How This Code Compares
With a work RVU of 3.45, this code ranks in the 24th percentile among Surgery codes — 2.3x below the median (8.00). The highest wRVU in this category is 106.19.
Specialties
Frequently Asked Questions
What is CPT code 54105?
CPT 54105 (Biopsy of penis) is a Surgery code. Surgical biopsy of the penis performed under general anesthesia, allowing deeper or more extensive tissue sampling.
What is the wRVU value for CPT 54105?
The work RVU for CPT 54105 is 3.45. This code is primarily used by Urology, Surgical Pathology. It has a 10-day global period.
When is CPT 54105 used?
Used when office biopsy insufficient or lesion located deeper. Allows adequate tissue sampling for diagnosis.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.