81415 Exome sequence analysis
Also known as: exome sequencing, whole exome analysis, WES
Whole exome sequence analysis for genetic disease evaluation, proband analysis only.
In Plain Language
genetic test looking at all genes; comprehensive gene sequencing test
Clinical Context
Sequence analysis of all protein-coding regions of the genome; used for diagnosis of genetic disorders when etiology is unclear.
RVU Information
CPT 81415 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.
Specialties
Frequently Asked Questions
What is CPT code 81415?
CPT 81415 (Exome sequence analysis) is a Pathology & Lab code. Whole exome sequence analysis for genetic disease evaluation, proband analysis only.
Who uses CPT code 81415?
CPT 81415 is used by genetics, molecular pathology, clinical genetics. Sequence analysis of all protein-coding regions of the genome; used for diagnosis of genetic disorders when etiology is unclear.
When is CPT 81415 used?
Sequence analysis of all protein-coding regions of the genome; used for diagnosis of genetic disorders when etiology is unclear.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.