88309 Tissue examination by pathologist
Also known as: tissue exam, comprehensive histopathology
Microscopic examination of tissue sections (26 or more blocks) by a pathologist for extremely complex surgical specimens.
In Plain Language
very extensive tissue examination; comprehensive specimen analysis
Clinical Context
Maximum complexity examination for extremely extensive specimens with multiple tissue types, organs, or special sampling requirements.
RVU Breakdown
| Work RVU | 2.73 |
| Total RVU | 2.73 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
With a work RVU of 2.73, this code ranks in the 99th percentile among Pathology & Lab codes — 4.0x the median (0.68). The highest wRVU in this category is 2.78.
Specialties
Frequently Asked Questions
What is CPT code 88309?
CPT 88309 (Tissue examination by pathologist) is a Pathology & Lab code. Microscopic examination of tissue sections (26 or more blocks) by a pathologist for extremely complex surgical specimens.
Who uses CPT code 88309?
CPT 88309 is used by Surgical Pathology, Pathology. Maximum complexity examination for extremely extensive specimens with multiple tissue types, organs, or special sampling requirements.
When is CPT 88309 used?
Maximum complexity examination for extremely extensive specimens with multiple tissue types, organs, or special sampling requirements.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.