78110 Plasma volume single
Also known as: plasma volume study single, blood volume measurement
Plasma volume measurement using single injection technique and nuclear medicine methods to quantify circulating plasma volume.
In Plain Language
blood plasma measurement; plasma volume test
Clinical Context
Measures absolute plasma volume to differentiate true polycythemia from relative increases in red cell mass. Used in evaluation of suspected myeloproliferative disorders.
RVU Breakdown
| Work RVU | 0.19 |
| Total RVU | 0.19 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
Radiology codes require a written order, clinical indication, and a formal interpretation report. The professional component (modifier -26) and technical component (modifier -TC) may be billed separately.
How This Code Compares
With a work RVU of 0.19, this code ranks in the 9th percentile among Radiology codes — 4.3x below the median (0.81). The highest wRVU in this category is 11.57.
Specialties
Frequently Asked Questions
What is CPT code 78110?
CPT 78110 (Plasma volume single) is a Radiology code. Plasma volume measurement using single injection technique and nuclear medicine methods to quantify circulating plasma volume.
Who uses CPT code 78110?
CPT 78110 is used by Nuclear Medicine, Hematology, Radiology. Measures absolute plasma volume to differentiate true polycythemia from relative increases in red cell mass. Used in evaluation of suspected myeloproliferative disorders.
When is CPT 78110 used?
Measures absolute plasma volume to differentiate true polycythemia from relative increases in red cell mass. Used in evaluation of suspected myeloproliferative disorders.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.