78111 Plasma volume multiple
Also known as: plasma volume study multiple
Plasma volume measurement using multiple injection technique to assess total plasma volume with enhanced accuracy.
In Plain Language
repeated plasma volume measurement
Clinical Context
Multiple time-point plasma volume assessment for more accurate quantification, particularly in patients with abnormal fluid distribution.
RVU Breakdown
| Work RVU | 0.21 |
| Total RVU | 0.21 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
Radiology codes require a written order, clinical indication, and a formal interpretation report. The professional component (modifier -26) and technical component (modifier -TC) may be billed separately.
How This Code Compares
With a work RVU of 0.21, this code ranks in the 13th percentile among Radiology codes — 3.9x below the median (0.81). The highest wRVU in this category is 11.57.
Specialties
Frequently Asked Questions
What is CPT code 78111?
CPT 78111 (Plasma volume multiple) is a Radiology code. Plasma volume measurement using multiple injection technique to assess total plasma volume with enhanced accuracy.
Who uses CPT code 78111?
CPT 78111 is used by Nuclear Medicine, Hematology, Radiology. Multiple time-point plasma volume assessment for more accurate quantification, particularly in patients with abnormal fluid distribution.
When is CPT 78111 used?
Multiple time-point plasma volume assessment for more accurate quantification, particularly in patients with abnormal fluid distribution.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.