78121 Red cell mass multiple
Also known as: red cell mass multiple, RBC mass study multiple
Red blood cell mass measurement using multiple injection technique for comprehensive erythrocyte volume assessment.
In Plain Language
multiple red blood cell measurements
Clinical Context
Multi-time point red cell mass quantification with enhanced accuracy for complex hematologic disorders or verification studies.
RVU Breakdown
| Work RVU | 0.31 |
| Total RVU | 0.31 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
Radiology codes require a written order, clinical indication, and a formal interpretation report. The professional component (modifier -26) and technical component (modifier -TC) may be billed separately.
How This Code Compares
With a work RVU of 0.31, this code ranks in the 21st percentile among Radiology codes — 2.6x below the median (0.81). The highest wRVU in this category is 11.57.
Specialties
Frequently Asked Questions
What is CPT code 78121?
CPT 78121 (Red cell mass multiple) is a Radiology code. Red blood cell mass measurement using multiple injection technique for comprehensive erythrocyte volume assessment.
Who uses CPT code 78121?
CPT 78121 is used by Nuclear Medicine, Hematology, Radiology. Multi-time point red cell mass quantification with enhanced accuracy for complex hematologic disorders or verification studies.
When is CPT 78121 used?
Multi-time point red cell mass quantification with enhanced accuracy for complex hematologic disorders or verification studies.
Track This Code in RVU Edge
Log procedures, calculate wRVUs, and benchmark against national data — all in one app.
CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.