45335 Sigmoidoscopy with submuc injection
Also known as: sigmoidoscopy with submucous injection, flexible sig with saline lift
Sigmoidoscopy with submucosal injection of saline, medication, or epinephrine for lesion elevation or hemostasis.
In Plain Language
injection under polyp to lift it; medication injection in bowel wall
Clinical Context
Used for elevation of polyps prior to snare polypectomy or for hemostasis of bleeding lesions via epinephrine infiltration.
RVU Breakdown
| Work RVU | 1.01 |
| Total RVU | 1.01 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
As a surgical CPT code, proper documentation must include the operative report detailing the procedure performed, patient positioning, approach, findings, and any complications. This code has a 0-day global period, meaning pre- and post-operative E&M visits are billable separately on the same day. Ensure the diagnosis code (ICD-10) supports medical necessity for the procedure.
How This Code Compares
With a work RVU of 1.01, this code ranks in the 4th percentile among Surgery codes — 7.9x below the median (8.00). The highest wRVU in this category is 106.19.
Specialties
Frequently Asked Questions
What is CPT code 45335?
CPT 45335 (Sigmoidoscopy with submuc injection) is a Surgery code. Sigmoidoscopy with submucosal injection of saline, medication, or epinephrine for lesion elevation or hemostasis.
What is the wRVU value for CPT 45335?
The work RVU for CPT 45335 is 1.01. This code is primarily used by Colorectal Surgery, Gastroenterology, General Surgery.
When is CPT 45335 used?
Used for elevation of polyps prior to snare polypectomy or for hemostasis of bleeding lesions via epinephrine infiltration.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.