45381 Colonoscopy submucous njx
Also known as: colonoscopy with submucous injection, colon submucous lift, colonoscopy with submucosal injection
Colonoscopy with submucosal injection of saline, medication, or epinephrine for polyp elevation or hemostasis.
In Plain Language
injection under polyp to lift it; saline lift for polyp removal
Clinical Context
Used for elevation of polyps prior to snare polypectomy or for hemostasis via epinephrine infiltration of bleeding lesions.
RVU Breakdown
| Work RVU | 3.47 |
| Total RVU | 3.47 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
As a surgical CPT code, proper documentation must include the operative report detailing the procedure performed, patient positioning, approach, findings, and any complications. This code has a 0-day global period, meaning pre- and post-operative E&M visits are billable separately on the same day. Ensure the diagnosis code (ICD-10) supports medical necessity for the procedure.
How This Code Compares
With a work RVU of 3.47, this code ranks in the 24th percentile among Surgery codes — 2.3x below the median (8.00). The highest wRVU in this category is 106.19.
Specialties
Frequently Asked Questions
What is CPT code 45381?
CPT 45381 (Colonoscopy submucous njx) is a Surgery code. Colonoscopy with submucosal injection of saline, medication, or epinephrine for polyp elevation or hemostasis.
What is the wRVU value for CPT 45381?
The work RVU for CPT 45381 is 3.47. This code is primarily used by Colorectal Surgery, Gastroenterology, General Surgery.
When is CPT 45381 used?
Used for elevation of polyps prior to snare polypectomy or for hemostasis via epinephrine infiltration of bleeding lesions.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.